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Doctors Used to Prescribe Specific Brands Credit: Reddit It sounds unbelievable now, but cigarette ads once featured doctors in white coats endorsing specific brands

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It was the brainchild of Brendan O'Regan, a comptroller at the minuscule Shannon Airport, a popular re-fuelling spot for flights ferrying celebrities (the only people who could afford transatlantic air travel back then) between the U.S

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Interestingly, while downregulation of HIF-1 under hypoxia was accompanied by higher levels of hydroxylated HIF-1, HIF-1 hydroxylation was even downregulated by CSE under normoxic conditions